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Montelukast
Clinical data
Trade namesSingulair, others
AHFS/Drugs.comMonograph
MedlinePlusa600014
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth
Drug classLeukotriene receptor antagonist
ATC codeR03DC03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability63–73%
Protein binding99%
MetabolismLiver (CYP2C8-major, CYP3A4 and CYP2C9-minor) [1]
Elimination half-life2.7–5.5 hours
ExcretionBiliary

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Ayoclinic. rg/drugs-supplements/montelukast-oral-route/precautions/drg-20064902 Copyright 2020 IBM Watson Health.0 As medians ranges for Tmax, and t1/2 Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion.

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Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers.It may also be used as an adjunct therapy in symptomatic treatment of mastocytosis.

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